Products for Wnt Research Wnt Signaling Pathways Wnt ligands are a large family of secreted glycoproteins that have a central role in many processes involved in embryonic development and adult tissue homeostasis. The biological effects of Wnt ligands are mediated through an increasingly complex interplay of Wnt receptors, transmembrane regulators, and soluble inhibitors. The combination of these proteins are critical in .. 더보기 Myeloid-derived Suppressor Cells Myeloid-derived Suppressor Cells Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid progenitor cells that fail to differentiate into granulocytes, macrophages, and dendritic cells. These immature cells have the capacity to suppress immune responses mediated by natural killer cells, CD8+ and CD4+ T cells. MDSCs accumulate in the blood, bone marrow, and sec.. 더보기 B Cells B Cells B lymphocytes (B cells) are an integral part of the humoral immune response due to their ability to produce antibodies against foreign antigens. B cells originate from hematopoietic stem cells (HSCs) in the bone marrow, which is seeded during embryonic development by HSCs from the fetal liver. The initial stages of B cell development are antigen-independent and involve the generation of .. 더보기 이전 1 2 3 4 5 6 7 ··· 112 다음 목록 더보기
